The ablative of separation means "from": after verbs of freeing, lacking and departing and after adjectives such as liber, immunis, alienus, with or without a, ab, e, ex.
Verbs: libero, solvo "free from", careo "lack", abstineo "keep from", excedo, discedo "depart from": humanis … excedere "to depart from human affairs", corpore soluta "set free from the body".
Adjectives: liber, immunis, vacuus "free from", alienus "foreign to, apart from": temeritate omni liberam "free from all rashness", affectibus immunem "free from passions".
With persons, and often with places, a preposition is added (a, ab, e, ex, de): e vita … discedere "to depart from life", alienis a communione humana "foreign to human fellowship".
absque + ablative = sine "without": absque naturae ope "without the help of nature". Some words of lacking and sharing take the genitive instead: expers "without" (judicii expers "lacking judgement"), particeps "sharing in".